MESPT was started as a government programme (Micro Enterprises Support Programme -MESP), funded by the European Union. The Programme was implemented from December 1997 to December 2003. In 2002, a Trust by the name Micro Enterprise Support Programme Trust (MESPT) was established officially as a development organization by the Government of Kenya and the European Union (EU). In 2007, the EU bequeathed its founder rights and status to the Royal Danish Embassy in Kenya, (DANIDA) who were enjoined through a Trust Deed of 2013.

The main goal of the Trust to date is to  support micro enterprise development, inclusive of agricultural production, agro-business and agro-processing to promote social, economic and environmentally sustainable growth through improving performance of value chains and their actors, increasing availability of financial services through wider and deeper delivery mechanisms and increasing trade opportunities through improved enterprise-level supply side management in business development services aimed at poverty alleviation through employment creation and sustainable micro-enterprises.